When it comes to products that go in your mouth, especially for patients already managing the effects of cancer treatment, safety and efficacy testing isn't optional. It's essential. Here's a closer look at the testing behind the Benova Mouth Rinse System's Step 1 and Step 2 rinses.
What NAMSA testing covered
Both Step 1 and Step 2 were independently tested by NAMSA, the primary source of testing for medical device products. NAMSA conducted three categories of biocompatibility testing on each step:
Oral toxicity was evaluated using a 7-day test that assesses whether a product causes toxic effects when introduced to the oral environment over a period of repeated exposure. Both Step 1 and Step 2 passed.
Sensitization was assessed using a maximization test that evaluates whether a substance has the potential to cause an allergic reaction with repeated exposure. Both steps passed.
Oral mucosal irritation was tested using a model with a 4-hour liquid exposure protocol designed to reflect realistic use conditions. Both steps passed.
It's worth noting that this testing applies specifically to the Benova Mouth Rinse System. Benova's Pain & Itch Relief Lotion is a separate product with its own distinct formulation and testing profile.
What this means in practice
Passing all three categories means the Benova Mouth Rinse System has been shown to be non-toxic, non-sensitizing, and non-irritating to oral tissue under rigorous independent testing. For clinicians recommending a rinse to patients with already-compromised oral health, that track record matters.
The full NAMSA reports are available on our Medical Professionals page.
The NAMSA testing establishes that the Benova Mouth Rinse System is safe and non-irritating — but that's only part of the story. For a closer look at the science behind how Benova works, including findings from a University of Alabama Capstone College of Nursing study on its mechanism of action, read A New Standard in Oral Mucositis Relief: The Science Behind the Benova Mouth Rinse System.